ABSTRACT
Many studies have reported an association between periodontal infections and some systemic diseases such as respiratory and cardiovascular diseases. Some studies found a direct association between chronic gastritis caused by Helicobacter pylori [HP] infection and poor periodontal health
Methods: In a cross-sectional study from November 2014 to December 2015 in Kerman, the largest province in southeast Iran, patients with dyspepsia who were candidate for diagnostic upper gastrointestinal [GI] endoscopy were included in our study. Decayed, Missing, and Filled Teeth [DMFT] index and Loe plaque index that are two popular indexes in dental epidemiology were used to assess the oral health by a dentist before the upper GI endoscopy. According to the Loe plaque index, score: 0= no plaque, score: 1= a film of plaque attaching to the free gingival border and near area of the tooth, score: 2= moderate reposition of deposits within the gingival pocket, score :3= plenty of soft matter within the gingival pocket +/- on the tooth and gingival border. Scores
Results: According to Sidney's classification 77 [89.5%] patients had superficial gastritis, 3 [3.5%] had atrophic gastritis, and 6 [7%] had intestinal metaplasia. HP was found in 80.2% of the gastric mucosal biopsy samples. There were not statistically significant relationship between Sidney's classification, presence of HP in gastric mucosal biopsies, and hygiene indicators [p>0.05]. No relation was found between the DMFT index and superficial gastritis, atrophic gastritis, and intestinal metaplasia [p>0.05]. Gastric infection with HP was found in 70%, 75%, and 100% of patients with mild, moderate, and sever DMFT index, respectively
Conclusion: Our study showed that there might be a relation between poor oral hygiene and gastric precancerous lesions. In addition, HP infection in gastric histopathology might be associated with periodontal disease
ABSTRACT
Background: Improving life is the main goal of therapeutic interventions for chronic diseases. Although we needed to determine quality of life by various variables. This study aimed to determine quality of life in patients with Irritable Bowel Syndrome [IBS] in Kerman
Materials and Methods: This is a cross sectional study of 143 patients with IBS referred to a specialist, assessed by IBS-QOL.34. Data analyzed by descriptive statistics, Pearson correlation coefficients, t-test and ANOVA, using SPSS software. p.Value <0.05 was considered as statistically significant
Results: In this study from 143 samples, 82 were females [57.3%] and 61 males [42.7%]. Quality of life score in patients was 37.16 +/- 16.72, and there was significant difference in terms of employment and education level [p.value<0.05]
Conclusion: Among patients with IBS, quality of life is far from desired. Therefore, health care providers should consider psychosocial support alongside medical management for achieving better quality of life in these patients
ABSTRACT
Small intestinal bacterial overgrowth [SIBO] may have a role in the pathophysiology of irritable bowel syndrome [IBS]. So, the aim of this study was to assess the association between SIBO and IBS by using glucose breath test [GBT] in Kerman city as the first study in Iranian population. 107 patients with IBS and 107 healthy individuals were enrolled in our study. All the participants underwent GBT. A peak of H2 values >20 p.p.m above the basal value after glucose ingestion was considered suggestive of SIBO. SPSS software version 17 was used for data analysis. P value < 0.05 was considered as statistically significant. Of the 107 patients with IBS, 40 had positive GBT [37.4%] compared with 14[12.1%] out of the 107 control participants [p< 0.001]. Dominant symptoms in patients with IBS were diarrhea in 36[33.6%], constipation in 12[11.2%], abdominal pain in 22[20.6%], bloating in 28[26.2%], and change in bowel habit in 9[8.4%] patients. There was not statistically significant difference among any of this IBS subgroups and positive GBT [p=0.44]. There is a positive association between IBS and SIBO. We suggest a Placebo-controlled bacterial eradication study for identifying the role of SIBO in IBS
ABSTRACT
Chronic constipation is a common problem worldwide that negatively impacts quality of life. Because of the effects of psychological and cultural factors on the function of the bowel tract and the vast variety of ethnicities and diet among the Iranian people, the present study describes the occurrence of constipation and its associated factors in Kerman, the largest city in Southeast Iran. This was a cross-sectional study conducted in Kerman, Iran from 2011 to 2012 that included 2191 adults who were randomly selected and interviewed face to face using a validated questionnaire based on Rome III criteria. Demographics, cigarette smoking, opium dependence, amount of fiber consumption, physical activity and psychological factors were assessed. Inclusion criteria was ages 15 to 85 years old. Exclusion criteria was the presence of any metabolic and/or neuro-muscular disease that caused constipation. All data were analyzed with Stata11 software, with a confidence interval of 95%. A p-value of 0.2]. Although the prevalance of constipation in Iran is estimated to be lower than Western countries, new changes in life style can cause an increase in the burden of constipation in the future
ABSTRACT
The incidence of inflammatory bowel disease [IBD] varies among different societies. The aim of this study is to determine the incidence rate of IBD in Kerman, a city in Southeast Iran. All medical records that indicated a new diagnosis of ulcerative colitis [UC] or Crohn's disease [CD] were retrieved from the gastrointestinal endoscopy and pathology departments of 12 centers from October 2011 to September 2012. The incidence rate of UC in Kerman was estimated at 4.98/100,000 [95% CI: 2.44-6.94]. The mean age of patients was 39.4 years and male to female ratio was 0.89:1.0. UC patients had the following prevalence: cigarette smoking [30%], appendectomy [36%] and oral contraceptive [OCP] use [78.9%]. The incidence rate of CD was 0.8/100,000 [95% CI: 0.6 4-1.14]. The mean age at diagnosis was 33.3 years and male to female ratio was 0.5:1.0. Cigarette smoking was reported in 33.3%, appendectomy in 66.6% and OCP useing in 75% of CD patients. Rectal and distal colitis, left side colitis and extensive colitis was seen in 20 [55.4%], 12 [33.3%] and 4 [11.1%] of patients with UC, respectively. All patients with CD had large intestinal involvement and one case [16.6%] had ileocolonic disease. Our study has shown that the incidence rate of both UC and CD in Kerman is lower than Western populations but it is the same as some Asian countries. Characteristics of disease involvement in this study are similar to other studies that have been conducted in Iran and elsewhere.